GLP-1 Recomposition
Tirzepatide
Dual-agonist GLP-1/GIP for advanced recomposition. The highest trial averages, lean mass protected, with a real off-ramp.
Available by consultation
Clinical Overview
How Tirzepatide works
The first to engage two metabolic pathways at once — the reason its trial results set a new ceiling.
Engages the GIP receptor
Targets glucose-dependent insulinotropic polypeptide — a metabolic pathway most weight medications do not address.
Engages the GLP-1 receptor
Simultaneously mimics GLP-1 — suppressing appetite and slowing how quickly food leaves the stomach.
Combined metabolic effect
The dual mechanism produces the highest average weight loss recorded in any GLP-1-class trial to date.
Candidacy Profiling
Who it’s for
Adults who want the most advanced protocol — with the peptide stack and supervision that turn fast fat loss into true recomposition.
- Adults 18+ with a BMI of 27 or higher, or 25+ with weight-related conditions
- Patients who plateaued on a single-agonist GLP-1 and want to escalate under supervision
- Members optimizing for performance and longevity who want lean mass actively protected
- Personal or family history of medullary thyroid carcinoma or MEN 2
- Pregnancy, breastfeeding, or planning pregnancy
- Active pancreatitis or untreated severe gastrointestinal disease
Expected Timeline
What to Expect
It acts faster and reaches further than single-agonist GLP-1s. Your physician titrates the dose and stack to your body.
- 01
Month 1
Titration
Faster initial response than single-agonist GLP-1s. Careful dose escalation begins.
- 02
Month 3
Established
Therapeutic dose reached. Strong recomposition momentum; appetite consistently reduced.
- 03
Month 6
~20%
Average body weight reduction in published trials. Many members exceed this range.
- 04
Off-ramp
Sustained
A structured taper with reset peptides holds results for the majority of members who finish the program.
Outcomes referenced from SURMOUNT-1 trial data. Individual results depend on starting weight, dose, and adherence.
Your Concierge Support
Your care team
LunaRx is led by Anamaria Galvan, RN — eight years of clinical experience and ten years in pharmacy — alongside independent, U.S.-licensed physicians. Every protocol is physician-directed and built for recomposition: fat loss, lean-mass protection, and a clean off-ramp. Care is available in English and Spanish, with direct, secure messaging on your schedule.
- 01Compounded medication
- Prepared by partner compounding pharmacies and shipped on a structured cadence.
- 02Muscle-protective peptides
- Growth-hormone secretagogues, recovery, and NAD⁺ support stacked to defend lean mass.
- 03Physician-directed dosing
- Titration and adjustments at every transition under expert clinical supervision.
- 04Direct message access
- Reach your provider directly between check-ins — in English or Spanish — via your secure portal.
- 05Structured off-ramp
- A defined taper with GI-recovery and reset peptides so you finish the program and hold results.
- 06Discreet direct delivery
- Temperature-controlled, unmarked packaging delivered direct to your door.
The LunaRx Standard
Not weight loss. Recomposition — with an exit strategy built in from day one.
- 01.Precision, not mass-market
- We reject the commoditized cheap-generic approach. Every protocol is titrated to your physiology by a physician — dose, peptide stack, and timeline calibrated to you.
- 02.Protect the muscle
- GLP-1 alone can cost you lean mass. We pair it with muscle-protective and cellular-recovery peptides so the weight you lose is fat — and what stays is strength, skin, and vitality.
- 03.A real off-ramp
- Most platforms keep you on the drug forever. We design a structured taper paired with GI-recovery and metabolic-reset peptides, so you come off cleanly and hold your results.
Clinical Safety
Safety, first
Common side effects
Most common during titration: nausea, decreased appetite, and digestive changes. Typically mild and resolve as the body adjusts to each step in the protocol.
Clinical Contraindications
Not appropriate for patients with a personal or family history of medullary thyroid carcinoma or MEN 2, or for patients who are pregnant or breastfeeding. Full medical history is reviewed before any prescription is authorized.
LunaRx protocols are prepared by partner compounding pharmacies in the United States. Compounding pharmacies are regulated by both state boards and the FDA and have been part of American medicine since long before mass-manufactured drugs existed. The active ingredient is prepared per your protocol — supervised by your physician — and delivered direct to your door.
Clinical Experience
In their words
- “
I plateaued on semaglutide, and the switch to tirzepatide was a second wind. Down another twenty-two pounds — and my labs are better than they've been in a decade.
- “
The speed surprised me. What kept me here was the off-ramp plan — I always knew this had an ending, not a forever subscription.
- “
I'm a numbers person. The recovery peptides protected my strength while I dropped fat — my recomposition is real, not just a lighter version of tired.
Frequently Asked
Common questions
Two things: recomposition and an exit strategy. We pair GLP-1 therapy with muscle-protective peptides so the weight you lose is fat, not lean mass — and we design a structured off-ramp so you come off the medication cleanly instead of staying on it forever.
Yes. LunaRx is a bilingual practice — your intake, your provider messaging, and your care are available in English and Spanish. / Sí. Tu evaluación y tu atención están disponibles en inglés y español.
After an intensive fat-loss and lean-mass-protection phase, your physician systematically tapers your GLP-1 while pairing it with GI-recovery and metabolic-reset peptides — so your metabolism is supported through the transition and your results hold.
Your consultation is reviewed and authorized by an independent, U.S.-licensed physician. LunaRx is led by Anamaria Galvan, RN, with physician oversight on every protocol.
Memberships may be canceled with 30 days' notice prior to the next billing cycle. Consultations, medical visits, and fulfilled prescriptions are non-refundable once services begin or medication is processed.
Yes. LunaRx is HIPAA compliant. Your medical information is shared only with your assigned provider and the dispensing pharmacy. We never sell or share your data.
Comparison Protocol
Semaglutide
The foundational single-agonist GLP-1 program. Lower trial averages, often the right starting point.
Begin Consultation
Start with a conversation
Your consultation is reviewed by your dedicated provider. If authorized, your protocol is prepared by a partner compounding pharmacy and delivered direct to your door.